Construction Alert
Baltimore City is closing both eastbound lanes on Orleans Street from Broadway to Wolfe Street, beginning Tuesday, July 6, to install underground electrical ducts. To detour, you’ll have to turn left on Broadway, right on Monument, right on Wolfe and back to Orleans. This closure will last for approximately two weeks. The Orleans Street Garage will remain open from westbound Orleans.  Please allow extra time for this detour. Click here for a map of the Johns Hopkins Medical Campus.

Pilot Study of the Safety and Efficacy of Digitoxin to Suppress Inflammation in Cystic Fibrosis Trial Is Now Enrolling
The digitoxin trial is now enrolling patients aged 18 years and up in patients with CF. Digitoxin is an oral medication used in Europe for treatment of heart failure. It is known to decrease inflammation in the airways. A description of the study can be obtained by clicking here. For more information contact Karen Callahan, RN at 443-287-8983 or by e-mail.

Prediction by Ultrasound of the Risk of Hepatic Cirrhosis in Cystic Fibrosis (PUSH) is Now Enrolling Children Aged 3-12 Years Old
The purpose of this research study is to learn more about liver disease in people with cystic fibrosis (CF) using a test called a liver ultrasound.  The liver ultrasound test may help to diagnose and treat liver disease in people with CF.  In this 5-year study, participants will have labwork and complete questionnaires once a year and have a liver ultrasound test every two years. For more information contact Karen Callahan, RN at 443-287-8983 or by e-mail.

PTC124 Trial Is Now Enrolling
The PTC124 trial at Johns Hopkins is now enrolling patients aged 6 and up with CF. PTC124 is an oral medication designed to help patients with nonsense CFTR mutations. This would be anyone with the letter ‘X’ in their mutation name. A description of the study can be obtained by clicking here. For more information contact Karen Callahan at 443-287-8983 or by e-mail.

Hear Dr. Eitan Kerem Speak About PTC124
Dr. Kerem's presentation to the Johns Hopkins CF Center is online. Dr. Kerem is a world known leader in CF research who has been at the forefront of the development of PTC124. Click here to view the presentation.

The Family Day Talks Are Online
The Johns Hopkins Annual CF Family Education held on  November 21st was a great success. You can view all the lectures by clicking here. All four talks can be viewed including: Introductory remarks by Dr. Mogayzel; Exercise and CF by Dr. Paranjape; An Adult Patient Perspective by Chris Dopher and the keynote address by Dr. Robert Beall, President and CEO of the CF Foundation on the Future of CF Research.