Summer 2007 Studying the Science of Resistance Pseudomonas aeruginosa is a nasty bug, infecting nearly 80 percent of all CF patients. And its success lies in its ability to resist many common antibiotics thrown at it. In fact, although immediate treatment with antibiotics can clear the infection, in many cases the bacteria adapt and establish permanent colonies in the lungs, increasing sputum production and decreasing lung function. Fall 2006 Advancing the Knowledge A distinct advantage to being a patient of The Johns Hopkins Cystic Fibrosis Center is that the doctors you see regularly are contributing significantly to the understanding and management of cystic fibrosis worldwide. January 2006 Raising the Bar on CF Care Quality improvement sounds like a buzzword straight out of corporate America: how are we going to improve the quality of these widgets we’re building? September 2005 Piloting the Enterprise Master multi-taskers, research coordinators keep clinical trials running smoothly. January 2005 Environment, More than Genes, Influences CF Lung Disease Severity As scientists continue to learn more about the gene responsible for cystic fibrosis—CFTR—it is becoming clear that this genetic mutation alone does not determine why the severity of CF differs so much from person to person.

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