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People: William Guggino, PhD

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William B. Guggino
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William B. Guggino, PhD

Director, Cystic Fibrosis Research Development Program
Professor and Chariman of Physiology

Dr. William Guggino attended Long Island University and received his Ph.D. from the University of North Carolina. He is director of the NIH Heart, Lung, and Blood Institute, Cystic Fibrosis Gene Therapy Center. His current research is investigating the structure and function of CFTR and water channels, trafficking and molecular organization of transport proteins in epithelial cell membranes, and genetic therapies for the correction of defective ion transport in CF cells and patients. Research is also being conducted on the identification of the specific defect in CFTR channel regulation in CF patients.

Research Interests

  • Ion channels

  • Gene therapy
  • Polycystic kidney disease
  • Epithelial cell biology
  • Protein trafficking